Lipogaine for Women: Review

Lipogaine is a minoxidil-based topical hair loss treatment. As the only FDA-approved treatment for hair loss in women, Minoxodil more recognizably is sold under the name of Rogaine.

Lipogaine claims to be a huge improvement on this popular hair loss treatment.

Compared to Rogaine, the Lipogaine solution that contains wider variety of ingredients that help with female hair loss. (Lipogaine also offers a robust product line for men).

Also, for those of us with sensitive scalps, Lipogaine claims to be a more tolerable formulation for our finicky skin.

Because I and probably most of my readers have a sensitive scalp, I will be focusing on that version of Lipogaine for Sensitive Scalp in this review.

What’s in Lipogaine?

First off, what’s NOT in Lipogaine:  propylene glycol. This is the ingredient responsible for so much of the scalp irritation experienced by those who have tried and ultimately set aside Rogaine.

Lipogaine contains the following ingredients:

Minoxidil: Minoxidil is the FDA approved and most widely used ingredient in hair regrowth products as of today. It was first used as an oral drug to lower blood pressure. It was soon found to stimulate hair growth.

Rigorous clinical studies have confirmed this “side effect” and its FDA approvals for hair re-growth as topical solutions were granted.

AzetinolTM: A proprietary extract of natural grains. Grains rich in fatty acids, linoleic acid, oleic acid, and vitamin A are processed and extracted to enrich powerful DHT blocking components.

Castor oil: Castor oil has long been used as a natural remedy to combat hair loss and help hair grow fast. It’s antibacterial and anti fungal properties make it beneficial against folliculitis, dandruff and scalp infections, the common cause for hair loss. Caster oil is rich in ricinoleic acid, which helps increase circulation to the scalp and improve hair growth.

Ricinoleic acid also helps balance scalp pH and replenish the scalp’s natural oils and undo some of the damage of harsh chemical hair products. The antioxidants in castor oil also support the keratin in hair and help make hair stronger, smoother and less frizzy.

In the 2014 study published in British Journal of Dermatology, a team of renowned academic researchers discovered that hair follicles extracted from human males in presence of low concentration of caffeine showed significant hair growth and prolonged growth phase compared to the hair follicles cultured in pacebo solution.

The study found the caffeine also had a beneficial effect on female hair growth as well. Currently there are caffeine based hair loss shampoo from a number of different companies such as  Men+Care Thick & Strong Fortifying 2 in 1 Shampoo + Conditioner by Dove, and Alpecin shampoo by Dr. Kurt Wolff GmbH.

Saw Palmetto: (Serenoa repens or Sabal serrulata): A dwarf palm plant native to North America. It primarily grows along the Atlantic coast in Georgia and Florida. The active ingredients are believed to be found in the plant’s brown-black berries.

It’s a popular dietary supplement for conditions associated with benign prostate gland enlargement (called benign prostatic hyperplasia, or BPH).

Study shows Saw Palmetto may work similarly to finasteride. [Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study. Int J Immunopathol Pharmacol. 2012 Oct-Dec;25(4):1167-73.]

BiotinOne of the most important vitamins that improve the nail cell health and skin cell. It was discovered that certain foods contain this vitamin, and if you do not have it in sufficient quantity  hair and nails become brittle.

The oil was used traditionally to treat a variety of skin diseases. Its natural properties are a tremendous boon for a scalp plagued by dandruff and irritation.

Argan oil is rich in natural phenols that are beneficial to hair follicles. Not only does it promote new hair growth, but also will help you grow healthy, thick looking hair.

Many beauticians and dermatologists recommend Argan oil as a cosmetic treatment for the hair and skin. We recommend Argan oil for a healthy head of hair alongside the big three hair loss treatment regimen.

Emu Oil: An anti-inflammatory natural tissue nutrient, full of healthy omega oils that support heal and rejuvenate the skin, as well as deeply moisturize. A recent Boston University study found that emu oil “remarkably” increased the thickness of the scalp skin and awakened dormant hair follicles.

Retinol: studies showed that combining minoxidil and retinol works better than minoxidil alone due to the enhanced penetration of minoxidil and improved scalp condition [Yoo HG et al, “the additive effects of minoxidil and retinol on human hair growth in vitro.” Bio Pharm Bull. 2007, 20(1): 21-6].

Procyanidin Oligomers: Naturally derived ingredients that have shown to stimulate hair growth similarly to Minoxidil. Research studies have shown that procyanidin oligomers possess growth stimulation activity toward hair epithelial cells in vitro and stimulate anagen induction in hair follicles in vivo.

GLA, ALA,  Linoleic Acid, and Oleic Acid: Gamma Linolenic Acid (GLA), Alpha Linolenic Acid (ALA),  linoleic and oleic acid are essential fatty acids found in plant oils, which have been demonstrated to interferes the binding of DHT to proteins in in vitro study. Additionally GLA, ALA and oleic acid also presents some anti-inflammatory properties.

What does all that mean?

Looking further into this, I realized how much each ingredient works to enhance the effectiveness of Lipogaine as a whole.

Who knew that minoxidil alone could not be as effective if not combined with retinol: the combination of the two has far better results of improving scalp condition than using minoxidil alone. The mixture of minoxidil and retinal allows for deeper penetration of minoxidil in the skin.

Even AzenitolTM,  due to its properties containing fatty acids such as linoleic acid, oleic acid, and vitamin A, is a strong DHT blocker that works in harmony with minoxodil.

In summary, Lipogaine took something tried and proven for hair loss treatment, Minoxidil, and beefed it up with all kinds of synergistic helpers to make it even more effective. Cool!

Why Choose Lipogaine?

The web is full of enthusiastic reviews for Lipogaine. Many of these reviewers describe their prior experiences with other hair loss and minoxidil-based product, and the success they have with Lipogaine.

There are several reviews specifically from African-American women citing its great effect on hair regrowth around their edges and temples. Very cool!

Generally speaking, many people see results in 1-2 months, along with a thickening of their hair and improvement of hair growing in temples and along the hairline.

The side effects of Lipogaine can include, but aren’t limited to, the side effects to Minoxidil.

For fewer than 1% of uses those can be: unwanted facial/body hair, dizziness, fast/irregular heartbeat, fainting, chest pain, swelling of hands/feet, unusual weight gain, tiredness, difficulty breathing especially when lying down.

Stop using any minoxidil product immediately if this happens.

Lipogaine for women (Sensitive) does not include propylne glycol, which is responsible for many of the common negative reactions to other minoxidil formulations.

Also, Lipogaine (excluding only Lipogaine Shampoo) contains alcohol, which will cause burning or irritation of the eyes. If the hair regrowth solution accidentally gets into your eyes, rinse thoroughly with cool tap water.

lipogaine applicatorHow to Use Lipogaine:

Lipogaine is applied to dry hair (or towel dried hair which is less than 2 inches long). You may wash your hair 3 hours after applying the solution.

The included dropper applicator makes Lipogaine easy to use. Just fill the dropper up to the desired amount, and proceed to move the dropper close to the area you wish to treat.

Slowly squeeze the solution out, so that it does not run directly off the scalp.

Be sure the solution comes into contact with the scalp and not just the hair. This is crucial, so that the solution can be absorbed into the scalp around the thinning areas.

Use your fingertips to rub it into your scalp – the whole process just takes a few minutes.

Sometimes Lipogaine leaves a little residue, and in this case it’s best to use it at night before bed and simply wash it out in the morning.  Also noteworthy: this product has no smell.

Thoughts about Lipgaine, Rogaine, or any other way to hair gain (hehe)? I’d love to hear your thoughts, ideas, comments, feedback, questions, and random musings about anything at all. Leave a comment and I’ll get back to you soon!

30 thoughts on “Lipogaine for Women: Review”

  1. Great review! I love how you provide a lot of detail, especially about the ingredients in the product. The fact that is contains an FDA approved ingredient makes me much more interested in buying this. The results seem fast according to the reviews and I like that there are reviews from African American women, I don’t find many products like this. Thanks for the info!

  2. Your article is very useful.
    Each description of the ingredient is easy to understand. I will promote this product to my grandma who suffers from hair loss.
    Thank you.

  3. Hey cool review, I was thinking about using the Lipogaine for men product, I’m glad there’s is a link. =)

    Question: Even though I have a full set of thick hair, do you think it’s cool if I use this sometimes? I won’t abuse it, It would be for maintenance purposes.

    BTW, I’m glad their is NO propylene glycol in the Lipogaine product line. Did you know that propylene glycol is an ingredient in anti-freeze?

    • ANTI-FREEZE? holy crap, I didn’t know that. And yes, it’s best to start using hair loss products before your hair is totally gone, to keep your follicles alive and cranking!

      • Yes using hair loss products before matter at hand is an excellent idea, it’s kinda like hair insurance. You’re follicles are in good hands. 😉

  4. I didn’t know there was a product specifically for women’s hair regrowth. I like the fact that there are good reports for the areas around the sides of your face where if you wear your hair in a ponytail the strands can break off. Good to know.

    • Yeah, there are LOTS of products specifically for women’s hair loss and regrowth, because the causes for our hair loss can be different than for men. And yes, this can help with hair loss due to certain hair styles. thanks for visiting!

  5. Hi
    Very descriptive article about the ingredients, there benefits, combinations and possible side effects.It’s not only a review but detailed article about Lipogaine. The cost is affordable and worth trying this product.
    Most important is it has FDA approved ingredients and are mostly natural.I will definitely recommend Lipogaine to my friends who are having scalp problem. It seems it is good for fungal infection and dandruff of the scalp.
    Would you recommend this for men too?

    • Thanks for the question! Yes, there is a Lipogaine for Men product line and I would also recommend it. Seems fairly similar to the product for women but with the same benefits of these great ingredients and sensitive scalp forumlation.

  6. Great review penelope! this product looks to be really gentle on the scalp which is something i think a lot of people suffer from, my sister has really sensitive skin particularly on her scalp and she has to wash her hair with a special shampoo or her whole scalp will go red and itchy. I will pass this on to her as she was saying to me the other day that her hair was coming out when she was brushing it!
    thanks for the great info!

    • Wow, I’m glad you found some good info and it absolutely sounds like your sister needs to start treating her hair loss (while her follicles are still salvageable and not totally dead).

  7. Hi,

    I’ve had very bad loss for about 4 years now, due to a lot of different factors. in the last year it has gotten better, but now I’m working on regrowth. I have very light patches on the back of my head, would you recommend this product to try and restore hair on those parts?

  8. Hello!
    What a great article. I so appreciated how your explained the ingredients and how they work .In this day and age it is so important to read labels. Don’t you think?
    I will certainly recommend this article to anyone I know who is having a hair loss dilemma.
    This is such a thorough and engaging article to read. I learned something new!
    Many thanks, great job! ariel

  9. Thank you for this awesome article! It’s nice to see that there are products out there for women as well!

    I had never heard of Castor Oil for hair growth! That’s awesome!

    Having reached my 40’s, one thing I have noticed is that my hair is beginning to thin… I also did have a full hysterectomy 12 years ago which could have something to do with it. Very interested in this product. Maybe after the holidays I will come back for a purchase!

    Thanks again for this valuable information!

    Have a very, Merry Christmas and Happy New Year!

    • Hi Misty, thanks so much for the comment, and glad you could learn some new stuff about hair loss and hair growth options. happy holidays!!

  10. Penelope, you have such a great site. Thank you for sharing this opportunity to everyone. Hair loss is an ongoing problem among women, men and children. But is prevalent among aging men and women. I can benefit from this product and I will surely refer others to this site.
    Happy holidays!
    Louisa B

  11. Hi
    there’s a lot of good information about the product, but quick question what do you term as hair loss? is it naturally thinning hair over time or hair loss in specific areas?

    • Hi Savita, thanks for the great question. Hair loss has lots of different manifestations – for some people, it’s a bald spot, for others, it’s a thinning hair line or thinning regions. And for even others, it’s an overall thinning of the hair.

  12. Lipogain for woman must be amazing and I am going to use it for sure, as a mum of two I rarely get time to take bare of my self. This product looks amazing not only for healthy hair and growth but also for overall health. Thank you Penelope for sharing this amazing product.

    • Thanks for the feedback! It is nice to see a viable minoxodil-based alternative to Rogaine, especially the formulation for sensitive scalps.

  13. I had no idea what lipogaine was….im surprised by the amount of enhancing ingredients it has :O
    And for all the benefits it provides i think its great there has been only 1% of people that encounter side effects, it one of the lowest percents i have seen in a product.
    I have a friend that could really use this, i will pass it on!
    I really enjoy reading your reviews 🙂

    • Thanks for passing on your thoughts and also passing the info onto your friends! Yes, I agree, the incidence of side effects is super low for Lipogaine and that’s one of the most attractive things about it.

  14. You mentioned that it’s best to use it at night before bed and simply wash it out in the morning. That would be more than 3 hours, will that have a negative impact on the hair or will it do the opposite? And in case you suffer from dandruff is it still recommended to use? I have used some products that irritated my scalp afterward and I’m very careful selecting new products.

    • Thanks for the great question. The three hour mark is the minimum you should leave in Lipogaine, and there is no damage or risk from leaving it out overnight. I didn’t see anything about Lipogaine causing or interferring with dandruff in user reviews, but dandruff is such a case by case issue, I can’t make any general pronouncements about it…my best advice is to try it out and then if you find it to be irritating in any way, return for a refund. It also wouldn’t hurt to use this in combination with a dandruff shampoo!

  15. Hello Penelope, you mentioned that lipogaine does not contain propylene glycol, but I went to and I found this on their FAQ page “What are the most common side effects with the Lipogaine hair regrowth solution?

    Answer: The most common side effects are itching and scalp irritation of the treated area due to the use of propylene glycol.
    I’m very disappointed.

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